1.Zvikamu zvekutanga zvepiritsi yepiritsi
Punch uye kufa: Punch uye kufa ndizvo zvikamu zvekutanga zvepiritsi, uye imwe neimwe yezvibhakera inoumbwa nezvikamu zvitatu: yepamusoro punch, yepakati kufa uye yakaderera punch.Chimiro chepamusoro uye chepasi punches chakafanana, uye madhayamita emapuranga akafananawo.Zvibhakera zvepamusoro nepasi zvibhakera zvinofananidzwa nemaburi emufa wepakati anofa, uye anogona kutsvedza kumusoro nekudzika zvakasununguka pakati pegomba rekufa, asi hapazove nemapundu apo hupfu hunogona kubuda..Saizi yekugadzira kufa ndeye yakabatana saizi saizi, inochinjika.Madimikira ekufa anomiririrwa nedhayamita yepunch kana dhayamita yepakati kufa, kazhinji 5.5-12mm, imwe neimwe 0.5mm ndeyekutsanangurwa, uye kune gumi nemana zvirevo zvakazara.
Iyo punch uye inofa iri pasi pekumanikidzwa kukuru panguva yekugadzira tableting, uye inowanzogadzirwa nesimbi inotakura (yakadai se crl5, nezvimwewo) uye kupisa kunorapwa kuvandudza kuoma kwavo.
Kune marudzi akawanda ezvibhakera, uye chimiro chepunch chinotarirwa nechimiro chaidiwa chehwendefa.Zvinoenderana nechimiro chechimiro chekufa, inogona kukamurwa kuita madenderedzwa uye akakosha maumbirwo (kusanganisira mapolygoni nemacurves);maumbirwo ezvikamu zvepunch flat, hypotenuse, shallow concave, deep concave uye yakazara.Flat uye hypotenuse punches anoshandiswa kudzvanya mahwendefa ecylindrical, asina kudzika concave punches anoshandiswa kudzvanya mahwendefa ebiconvex, akadzika concave zvibhakera anonyanya kushandiswa kumanikidza akavharidzirwa piritsi machipisi, uye zvibhakera zvakabatanidzwa zvinonyanya kushandiswa kudzvanya mahwendefa ebiconvex.Shaped flakes.Kuti zvive nyore kuziva nekutorwa kwemishonga, mavanga akaita sezita remushonga, chipimo chemushonga uye mitsara yakatwasuka uye yakachinjika inogona zvakare kunyorwa kumucheto kwechiso chefa.Pakumanikidza mapiritsi ezviyero zvakasiyana, kufa nehukuru hwakakodzera kunofanirwa kusarudzwa.
2.Kushanda kwekushanda kwepiritsi yepiritsi
Maitiro ekushanda kwetablet press anogona kukamurwa kuita zvinotevera:
① Iyo punch chikamu chepasi punch (chinzvimbo chayo chekushanda chiri kumusoro) chinopinda mugomba repakati kubva kumucheto wepakati wepakati buri kuti chivhare pazasi pegomba repakati;
②Shandisa adder kuzadza buri repakati nemushonga;
③ The punch part of the top punch (chinzvimbo chayo chekushanda chiri pasi) chinowira mugomba repakati kubva kumucheto wepamusoro wepakati buri, uye inodzika kune imwe sitiroko yekutsikirira hupfu kuita mahwendefa;
④Chibhakera chepamusoro chinosimudza kubva mugomba, uye chibhakera chepasi chinosimudzwa kuti chisundire piritsi kubva mukati meburi repakati kuti ripedze kuita piritsi;
⑤Sundira pasi kunzvimbo yekutanga uye gadzirira kuzadza kunotevera.
3.The musimboti tableting muchina
① Kudzora kurongeka.Mahwendefa akasiyana-siyana ane zvakasiyana-siyana zvinodiwa.Kugadziriswa kwedosi hombe kunowanikwa nekusarudza zvibhakera zvine madhayamita akasiyana siyana, sezvibhakera zvine madhayamita e6mm, 8mm, 11.5mm, uye 12mm.Mushure mekunge saizi yekufa yasarudzwa, iyo diki dhizaini inogadziriswa nekugadzirisa kudzika kweiyo yakaderera punch inosvika mukati megomba rekufa, nekudaro ichichinja hurefu chaihwo hwepakati kufa kwegomba mushure mekuvharirwa kumashure, uye kugadzirisa huwandu hwekuzadza kwemushonga mukati. gomba rekufa.Naizvozvo, panofanirwa kuve nemuchina wekugadzirisa iyo yekutanga chinzvimbo chepasi punch mugomba rekufa patafura yepiritsi kuti isangane neiyo dosage kugadzirisa zvinodiwa.Nekuda kwekusiyana kwevhoriyamu yakananga pakati pemabheji akasiyana eupfu kugadzirira, basa rekugadzirisa iri rakakosha.
Mukutonga kwedosi, musimboti wechiito cheanodyisa zvakare ane simba rakakura.Semuenzaniso, mushonga wegranular unovimba nehuremu hwayo uye unotenderedza zvakasununguka mukati megomba repakati, uye mamiriro ayo ekuzadza akasununguka.Kana nzira dzakawanda dzekumanikidzira dzekupinda dzikashandiswa, mishonga yakawanda inozadzwa mumakomba ekufa, uye mamiriro ekuzadza anozonyanya kuoma.
② Kudzora kukora kwehwendefa uye compaction degree.Chiyero chemushonga chinotarirwa maererano nemishonga uye pharmacopoeia uye haigoni kuchinjwa.Kwenguva yakatarwa yekuchengetedza, kuchengetedza uye kuparara, kumanikidzwa kweimwe dose kunodiwawo panguva yepiritsi, iyo inokanganisawo kukora uye kuonekwa kwehwendefa.Kudzora kudzora panguva yetablet kwakakosha.Izvi zvinowanikwa nekugadzirisa yakaderera huwandu hwepunch mugomba rekufa.Mimwe mitsipa yepiritsi haina chete kukwira nekudzika kwechibhakera chepamusoro nechepazasi panguva yekutepfenyura, asi zvakare ine ekumusoro neazasi mafambiro ezasi zvibhakera.
uye kufamba kwakabatana kwepamusoro nepamusoro pezvibhakera kunopedzisa tableting process.Nekudaro, iyo yekumanikidza regulation inonyanya kuzadziswa nemaitiro ekugadzirisa kukwira nekudzika kuyerera kuti uone kudzvanyirirwa uye kutonga.
Nguva yekutumira: May-25-2022